Three invited lectures and three presentations from the laboratories of Nano-Bioengineering and Hybrid Photonic Nanomaterials of NRNU MEPhI presented at two international forums on research and developments at the interface of photonics and nanotechnology

In early June two international forums on research and developments in photonic nanostructures and their applications in various fields, from solar energy utilization to biomedicine, were held in St. Petersburg, Russia: Photonic Colloidal Nanostructures: Synthesis, Properties, and Applications (PCNSPA 2018) and 5th International A.M. Prokhorov Symposium on Lasers in Medicine and Biophotonics в рамках 18th International Conference on Laser Optics (ICLO 2018). Researchers from the cluster of two international laboratories of NRNU MEPhI, the Laboratory of Nano-Bioengineering (LNBE) and the Laboratory of Hybrid Photonic Nanomaterials (LPNM), took part in both forums, where they made a total of six presentations, including three invited plenary lectures by the leading scientists of both laboratories.

The lecture by Professor Igor Nabiev at PCNSPA 2018 (Nabiev, I., Ramos-Gomes, F., Alves, F., Chames, P., Baty, D., Sukhanova, A. Advanced nanotools for imaging of solid tumors and circulating and disseminated cancer cells) demonstrated the advantages of nanoprobes consisting of fluorescent quantum dots and ultrasmall single-domain antibodies for detecting cancer markers as tools for early diagnosis. Special emphasis was made on the possibility of using two-photon excitation of fluorescent labels, which provides a substantial increase in the signal-to-background ratio and allows imaging of deep tissue areas.

The lecture by Professor Yuriy Rakovich (Melnikau, D., Govyadinov, A.A., Sánchez-Iglesias, A., Grzelczak, M., Liz-Marzán, L.M., Rakovich, Y.P. Chirality and magneto-optical effect in coupled organic-inorganic nanostructures) dealt with a novel approach to magneto-optical chemo- and biosensing based on circular dichroism spectroscopy of organic/inorganic hybrid structures consisting of dye molecules in J-aggregate states and plasmonic nanoparticles. In these structures, nonmagnetic organic molecules may exhibit magneto-optical response due to strong coupling between the J-aggregate exciton and the nanoparticle plasmon, leading to the formation of a hybrid state in which the exciton acquires magnetic properties.

The oral presentation by Yuriy Kuzishchin (Kuzishchin, Y.A., Martynov, I.L., Osipov, E.V., Chistyakov, A.A., Nabiev, I.R. Optimization of excitation and detection modes to detect ultra low quantity of semiconductor quantum dots based on cadmium selenide) became a follow-up to Professor Nabiev's lecture. The presentation dealt with the recently developed photodetector and method for processing the detected signal that allow effectively distinguishing the photoluminescence signal from quantum dots as parts of diagnostic nanoprobes against the background of autofluorescence of biological tissues and other noises.

The issue of plasmon–exciton hybrid materials explored in Professor Rakovich's lecture was further developed by Semyon Goncharov (Goncharov, S.A., Krivenkov, V.A., Samokhvalov, P.S., Nabiev, I., Rakovich, Y.P. Photoluminescence properties of thin-film nanohybrid material based on quantum dots and gold nanorods). The study that he presented has demonstrated that interaction between plasmonic nanoparticles and quantum dots in a film of the hybrid material dramatically increases the quantum yield of biexciton luminescence of the quantum dots. This phenomenon has practical implications for the fields where one-photon sources are required.

The presentation by Victor Krivenkov (Krivenkov, V.A., Samokhvalov, P.S., Chistyakov, A.A., Nabiev, I.R. Photoelectrochemical response from quantum dots-bacteriorhodopsin hybrid material under near-infrared two-photon excitation) described a recent study in the field of photovoltaics with the use of nano–bio hybrid materials. The authors have developed a material based on photosynthesizing bacterial membranes embedded with multishell quantum dots; the use of this material extends the spectrum of utilizable solar energy to the near infrared region due to two-photon excitation of quantum dots followed by nonradiative energy transfer to the bacteriorhodopsin protein generating a membrane potential.

The reports presented at PCNSPA 2018 will be published in the Optics and Spectroscopy, a peer-reviewed journal published in Russian and English and cited in the Web of Science, Scopus, and other databases.

Professor Nabiev also gave an invited lecture at the "Photonics and nanobiotechnology" section of the ICLO 2018 symposium (Sukhanova, A., Chames, P., Baty, D., Ramos-Gomes, F., Alves, F., Nabiev, I. Nanophotonic functional imaging and related nanotoxicity issues). In this lecture he analyzed the mechanisms of nanotoxicity, which still restricts the use of quantum-dot-based diagnostic nanoprobes to blood and biopsy tests. The solution of this problem, which underway in LNBE, will make it possible to design nanoprobes for in vivo applications and to use these nanostructures for targeted drug delivery to cells, which is of utmost importance in antitumor therapy.

Contacts:

Maria G. Korenkova, director of external relations (MGKorenkova@mephi.ru)
Laboratory of Nano-Bioengineering, Moscow Engineering Physics Institute
31 Kashirskoe shosse, 115409 Moscow, Russian Federation
http://www.lnbe.mephi.ru/en

Alexandra V. Korenkova, research engineer (alexandrav.korenkova@gmail.com)
Laboratory of Hybrid Photonic Nanomaterials, Moscow Engineering Physics Institute
31 Kashirskoe shosse, 115409 Moscow, Russian Federation
http://lpnm.mephi.ru/index.php/ru/

 
 
 
© 2012 Laboratory of Nano-BioEngineering