MULTIFUNCTIONAL STIMULUS-SENSITIVE MICROCAPSULES AND NANOCRYSTALS FOR EARLY DIAGNOSIS AND EFFICACIOUS TREATMENT OF LUNG AND BREAST CANCERS (State Contract no. 16.1034.2017/PCh)

In the course of applied research on Multifunctional Stimulus-Sensitive Microcapsules and Nanocrystals for Early Diagnosis and Efficacious Treatment of Lung and Breast Cancers (State Contract no. 16.1034.2017/PCh, Grant Agreement of May 31, 2017), a technology for fabrication of stimulus-sensitive polymer microcapsules containing excitonic nanoparticles has been developed and the possibility of obtaining a combined system based on the stimulus-sensitive polyelectrolyte microcapsules containing both magnetic and excitonic nanoparticles has been demonstrated.Studies have been carried out on preliminary characterization of the microcapsules, including the estimation of the dispersive properties of the system designed and testing of the functional capacity of the system. The fabricated stimulus-sensitive polymer microcapsules containing excitonic or both excitonic and magnetic nanoparticles are 3.0–6.0 μm in size; therefore, they can be used as theranostic agents intended for parenteral administration.

Contacts:

Principal Investigator of the project:
Prof. Igor R. Nabiev, PhD, DSc, leading scientist of LNBE (igor.nabiev@gmail.com)

Maria G. Korenkova, LNBE director of external relations (MGKorenkova@mephi.ru)

Laboratory of Nano-Bioengineering, Moscow Engineering Physics Institute
31 Kashirskoe shosse, 115409 Moscow, Russian Federation
http://www.lnbe.mephi.ru/en

 
 
 
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