LNBE staff members are presenting three statements at the highly representative 2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON/SibMedInfo)

Staff members of LNBE will participate in the 2015 SIBIRCON/SibMedInfo conference, to be held in Akademgorodok, Novosibirsk, Russia, on October 28–30, and will make three statements there. Selected proceedings of the conference will be published in the IEEE Xplore digital library indexed in the Web of Science and SCOPUS databases.

Sergey Dayneko, PhD, will present a review on Quantum Dot Lasing: The Possible Biodiagnostic Implications, which will deal with the possibility of lasing in quantum dots embedded in polymer microbeads and the prospects of using this effect for designing a new generation of sensors. The optical properties of quantum dots, principles of lasing, and the potential for using quantum-dot-encoded beads in ultrasensitive diagnostics will be discussed.

Professor Igor Nabiev, leading scientist of LNBE, will present two studies on the application of diagnostic nanoprobes based on fluorescent nanocrystals conjugated with single-domain antibodies to imaging cancer markers by immunohistochemical and flow-cytometric methods. These studies discuss the specific characteristics of single-domain antibodies and quantum dots as components of diagnostic probes and present experimental data demonstrating that both one-photon and multi-photon imaging and diagnostic methods employing these nanoprobes can be applied to clinical samples. The main advantages of the new generation of diagnostic probes are their deeper penetration into tissues and unprecedented sensitivity of optical detection, which allows single tumor cells and micrometastases to be detected in a cell population and makes it possible to detect many different cancer markers in a single test using a single clinical sample.

Contacts:

Prof. Igor Nabiev, PhD, DSc, leading scientist (igor.nabiev@gmail.com)

Sergey V. Dayneko, PhD, engineer (s.daineko@gmail.com)

Laboratory of Nano-Bioengineering, Moscow Engineering Physics Institute
31 Kashirskoe shosse, 115409 Moscow, Russian Federation

http://www.lnbe.mephi.ru/en

 
 
 
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