Three reports from LNBE accepted to be presented at SPIE Photonics Europe

Three reports from LNBE will be presented at the SPIE Photonics Europe international forum, to be held in Brussels, Belgium, this April.

An invited oral presentation of the Nanomedicine Group Development and potential applications of microarrays based on fluorescent nanocrystal-encoded beads for multiplexed cancer diagnostics is to be presented at the Biophotonics: Photonic Solutions for Better Health Care conference. The authors are developing microarrays for simultaneous detection of multiple biomarkers in which the advantages of suspension arrays are combined with those of QDs, whose specific spectral characteristics are optimal for multiplexed diagnostics. To date, the research group has engineered microarrays based on QD-encoded polystyrene beads carrying capture antibodies against some cancer-specific markers. These diagnostic systems proved to be effective and highly specific tools for early diagnosis of prostate cancer and breast cancer.

A presentation on Quantum dot surface ligands control photoinduced degradation of the nanocrystal optical properties by researchers of the Nano-Heterostructures and Nanochemistry groups has been included in the Nanophotonics conference.

The authors have studied ligand photooxidation on the surface of quantum dots (QDs) excited with pulse laser radiation. The deterioration of the QD optical characteristics has long been considered to result from photooxidation of the nanocrystals with molecular oxygen that is present in the solution, whereas the possible effects of the organic ligands covering the surface of the nanocrystals after their synthesis are usually not taken into account. The results of this study pave the way for new approaches to the improvement of the photostability of QD-based photonic and photovoltaic devices under extreme operational conditions.

The same groups will present a report on Photoluminescence of CdSe/ZnS quantum dots in a porous silicon microcavity. Microcavity-based devices are increasingly widely used in various fields from nanophotonics and laser physics to biology and medicine. QDs, with their unique spectral properties, seem especially promising as luminophores for these devices. The study to be presented at the conference is the first to analyze the QD photoluminescence spectra in porous silicon microcavities. The authors have demonstrated, in particular, that the QD characteristic photoluminescence decay time is considerably decreased in a porous silicon microcavity compared with the decay time in a solution.

Contacts:

Kristina I. Brazhnik, engineer (kris.brazhnik@gmail.com)

Victor A. Krivenkov, junior researcher (vkrivenkov@list.ru);

Igor L. Martynov, PhD, researcher (i.l.martynov@gmail.com);

Laboratory of Nano-Bioengineering, Moscow Engineering Physics Institute,
31 Kashirskoe shosse, 115409 Moscow, Russian Federation

http://www.lnbe.mephi.ru/en

 
 
 
© 2012 Laboratory of Nano-BioEngineering