Young researchers of LNBE have completed on-the-job training in a research center of Trinity College Dublin, Ireland

Four young researchers of LNBE took on-the-job training in a research center of Trinity College Dublin, Ireland in August 2013. Studies were carried out in two research groups under the supervision of leading researchers of the center. The training programs included both mastering the existing techniques developed by the Irish colleagues and the trainees' own research projects.

The main objects of the studies performed by Daria Solovyeva and Yuriy Kuzishchin in the Centre for Research on Adaptive Nanostructures and Nanodevices were structures based on purple membranes (PMs) and silver nanoparticles, as well as PMs and quantum dots (QDs). All the studies were carried out using a unique combined instrumental setup suitable for atomic force microscopy (AFM), confocal Raman/fluorescence microscopy, scanning near-field optical microscopy, and tip-enhanced Raman scattering analysis.

PMs with adsorbed silver nanoparticles were scanned using AFM, with the giant Raman scattering (GRS) spectrum simultaneously recorded for the selected area of a single membrane containing bacteriorhodopsin (bR). The result of this scanning was the first ever recorded GRS spectrum with a peak of the main form of the bR photocycle.

The structure of the PM–QD construction was also AFM-scanned to select the optimal area. This area was scanned again at a large scale (a 3´3 μm area), and the fluorescence of the PM sample with QDs on its surface was analyzed. Given the possibility of energy transfer from QDs to bR, the researchers measured the fluorescences of a single QD adsorbed on a substrate and a single QD adsorbed on a PM. The absence of fluorescence in the latter case was regarded as evidence of energy transfer from the QD to bR.

Kristina Brazhnik and Pavel Linkov, under the supervision of researchers of the Laboratory of Physics and Chemistry of New Materials headed by Prof. Yuriy Gunko, synthesized magnetic nanoparticles of magnetite (Fe3O4) and cobalt ferrite (CoFe2O4) with a high magnetic anisotropy. The synthesis of magnetic nanoparticles by means of chemical precipitation allows one to obtain samples of a desired size within a range from 5 to 500 nm that remain stable for a long time when exposed to air.

Samples of hybrid ultrasmall beads possessing both magnetic and fluorescent properties were obtained. This technology is promising for the development of highly sensitive suspension systems for diagnosis of various diseases. The system is unique in that magnetic properties may considerably simplify and accelerate the diagnostic procedures.

Trinity College Dublin is the leading Irish educational and research center, ranking the 110th in the Times Higher Education Supplement Global Ranking 2012 of the world's best higher education institutions.


Prof. Igor Nabiev, PhD, DSc., Leading Scientist of LNBE (

Laboratory of Nano-Bioengineering, Moscow Engineering Physics Institute, 31 Kashirskoe shosse, 115409 Moscow, Russian Federation

© 2012 Laboratory of Nano-BioEngineering