On-the-job training of young researchers in Dublin: Further development of LNBE international collaboration

Four young researchers of LNBE, Kristina Brazhnik, Daria Solovyeva, Yuriy Kuzishchin, and Pavel Linkov, took on-the-job training in a research center of Trinity College Dublin, Ireland. For a month, these researchers mastered the techniques used by their Irish colleagues and carried out their own studies under the supervision of leading researchers of the center. This program was part of collaboration between LNBE and Trinity College Dublin.

LNBE researchers were included in two research teams. The main purpose of the study performed by Daria Solovyeva and Yuriy Kuzishchin in the Centre for Research on Adaptive Nanostructures and Nanodevices was to analyze structures based on purple membranes (PMs) and silver nanoparticles, as well as PM–quantum dot (QD) systems. The data they have obtained will add to the current knowledge of the mechanisms of Förster resonance energy transfer and giant Raman scattering in the systems studied.

Kristina Brazhnik and Pavel Linkov mastered the methods of the synthesis of magnetic nanoparticles and functionalization of their surface under the supervision of Prof. Yuriy Gunko, the head of the Laboratory of Physics and Chemistry of New Materials. The magnetite and cobalt ferrite nanoparticles obtained by the chemical precipitation method are characterized by high magnetic moment and anisotropy. The possibility to obtain nanoparticles smaller than 10 nm without using any stabilizers is an important advantage of this method. In addition, Kristina Brazhnik has mastered the procedure for obtaining and modifying magnetic particles whose characteristics are comparable with those of the commercially available analogues, DynaBeads. Hybrid particles based on polymeric ultrasmall beads possessing both magnetic and fluorescent properties (determined, respectively, by the incorporated magnetic particles and fluorescent nanocrystals) have been engineered. The use of these microparticles can dramatically increase the sensitivity, accuracy, and quickness of detection of target molecules in biological samples.

The skills acquired by our researchers will allow them to perform the necessary stages of chemical modifications of the surface of nano- and microparticles, as well as to fabricate microparticles with the desired optical and magnetic characteristics.

The techniques mastered by the LNBE researchers make it possible to substantially extend the scope of research carried out in the Nanochemistry and Nanomedicine groups of LNBE.

© 2012 Laboratory of Nano-BioEngineering